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Wednesday, 5 pm CET, i.e, 11 am ET

 

Organized by David Hansel, Ran Darshan & Carl van Vreeswijk* 

*deceased

About Us

About the Seminar

VVTNS  is a weekly digital seminar on Zoom targeting the theoretical neuroscience community. Created as the World Wide Neuroscience Seminar (WWTNS) in November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), its aim is to be a platform to exchange ideas among theoreticians. Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars  are 45 min long followed by a discussion and are held on Wednesdays at 11 am EST. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.

 

To participate in the seminar you need to fill out a registration form after which you will

receive an email telling you how to connect.

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David Kleinfeld

UCSD

October 11, 2023

Vasomotor dynamics: Measuring, modeling, and understanding the other network in the brain

Much as Santiago Ramón y Cajal is the godfather of neuronal computation, which occurs among neurons that communicate predominantly via threshold logic, Camillo Golgi is the inadvertent godfather of neurovascular signaling, in which the endothelial cells that form the lumen of blood vessels communicate via electrodiffusion as well as threshold logic. I will address questions that define spatiotemporal patterns of constriction and dilation that develop across the network of cortical vasculature: First - is there a common topology and geometry of brain vasculature (our work)? Second - what mechanisms govern neuron-to-vessel and vessel-to-vessel signaling (work of Mark Nelson at U Vermont)? Last - what is the nature of competition among arteriole smooth muscle oscillators and the underlying neuronal drive (our work)? This answers to these questions bear on fundamental aspects of brain science as well as practical issues, including the relation of fMRI signals to neuronal activity and the impact of vascular dysfunction on cognition. Challenges and opportunities for experimentalists and theorists alike will be discussed.

Organizers

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David Hansel

I am a theoretical neuroscientist at the National Center for Scientific Research in Paris, France and visiting professor at The Hebrew University in Jerusalem, Israel. I am mainly interested in the recurrent dynamics in the cortex and 

basal ganglia.

Carl van Vreeswijk *

I am a theoretical neuroscientist working at the National Center for Scientific Research in Paris, France. My main interest is the dynamics of recurrent networks of neurons in the sensory system

*deceased

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Ran Darshan

 I am a theoretical neuroscientist working at the Faculty of Medicine, the Sagol School of Neuroscience & the School of Physics and Astronomy at Tel Aviv University, Israel. I am interested in learning and dynamics of neural networks. My main goal is to achieve a mechanistic understanding of brain functions.

©2020 by WWTNS

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